abstract：:The proximal tubule reabsorbs approximately 80% of the filtered load of bicarbonate. Defects in the process of bicarbonate reabsorption result in loss of bicarbonate and proximal renal tubular acidosis. Global proximal tubule dysfunction is known as the Fanconi's syndrome. Both isolated proximal renal tubular acidosis...

journal_title：Journal of nephrology

authors： Quigley R

更新日期：2006-03-01 00:00:00

abstract：:This review focuses on a series of risk factors involved in the pathogenesis of cardiovascular complications in patients undergoing Regular Dialysis Treatment (RDT). Many of them are not modifiable by any pharmacological strategies or dialysis therapy, others - such as phosphate overload - can be corrected successfull...

journal_title：Journal of nephrology

authors： Brancaccio D,Zoccali C

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Causes of hypertension and cardiac hypertrophy in hemodialysis (HD) patients are multiple, but the role of fluid overload appears to be crucial. Short daily HD (sDHD = 2 hr x 6/week) seems to allow reductions in left ventricular mass (LVM) through the reduction of extracellular water (ECW). Better cardiovasc...

journal_title：Journal of nephrology

authors： Fagugli RM,Pasini P,Pasticci F,Ciao G,Cicconi B,Buoncristiani U

更新日期：2006-01-01 00:00:00

abstract：:Henoch-Schonlein purpura is a clinical syndrome characterized by the association of skin, joint, and gastrointestinal symptoms. Henoch-Schonlein purpura is characterized by wide-spread vasculitis. Although the clinical symptoms of this disease are characteristic, the diagnosis is not always easy to establish because o...

journal_title：Journal of nephrology

authors： Ferrario F,Rastaldi MP

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is associated with increased morbidity and mortality in cardiovascular disease (CVD). Apart from traditional risk factors, chronic inflammation, oxidative stress, malnutrition and endothelial dysfunction are important in CVD development in renal patients. Our aim was to investiga...

journal_title：Journal of nephrology

authors： Annuk M,Soveri I,Zilmer M,Lind L,Hulthe J,Fellström B

更新日期：2005-11-01 00:00:00

abstract：INTRODUCTION:Post-transplant malignancies are among the most important complications in organ transplantation. Hemangioblastoma (HB) is especially prevalent in the cerebellum. CASE REPORT:A 20-year-old male who first started dialysis therapy, and then underwent kidney transplantation from a living-relative donor. Five...

journal_title：Journal of nephrology

authors： Oztürk S,Soyluk O,Görçin S,Alişir S,Güven D,Türkmen A,Sever MS

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:There have been many studies in recent years concerning the role of nitric oxide (NO) in acute renal failure (ARF). In this study, the effects of the inhibition or the induction of NO synthase (NOS) on gentamicin-induced ARF was investigated in isolated perfused rat kidneys. METHODS:Kidneys from male Spragu...

journal_title：Journal of nephrology

authors： Ghaznavi R,Faghihi M,Kadkhodaee M,Shams S,Khastar H

更新日期：2005-09-01 00:00:00

abstract：:We report a unusual case of idiopathic nodular glomerulosclerosis mimicking changes that develop in diabetic nephropathy. A 66-year-old non-diabetic female developed nephrotic range proteinuria and the work up was unremarkable. Light and electron microscopy showed mesangial expansion with Kimmelsteil-Wilson nodules an...

journal_title：Journal of nephrology

authors： Navaneethan SD,Singh S,Choudhry W

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:The regulation of renal hemodynamics is closely related to the L-arginine (L-Arg)/nitric oxide (NO) pathway. NO - metabolized from L-Arg - is capable of improving renal function in ischemic and toxic acute renal failure (ARF), while NO synthase (NOS) inhibition induces deterioration in renal function. The mo...

journal_title：Journal of nephrology

authors： Schramm L,Weierich T,Heldbreder E,Zimmermann J,Netzer KO,Wanner C

更新日期：2005-07-01 00:00:00

abstract：:A 59 year-old woman showed rapidly progressive glomerulonephritis during immunotherapy for metastatic renal cell carcinoma. She received unilateral nephrectomy and cytotoxic T lymphocyte (CTL) therapy for the treatment of retroperitoneal lymph node metastasis of renal cell carcinoma. With CTL therapy, her retroperiton...

journal_title：Journal of nephrology

authors： Kai H,Yamagata K,Usui J,Shimizu Y,Hirayama A,Yoh K,Mase K,Hirayama K,Nagase S,Nagata M,Kawai K,Akaza H,Koyama A

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Lipid peroxidation (LPO) plays a role in glomerulonephritis pathogenesis. The role of LPO in IgA nephropathy (IgAN) and the effect of prostaglandin E1 on it, is not determined. METHODS:Levels of malondialdehyde (MDA), superoxide dismutase (SOD) and vitamin E (vitE) were measured in 42 patients with IgAN and...

journal_title：Journal of nephrology

authors： Tian J,Chen JH,Li Q,He Q,Lin WQ

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:To report clinical symptoms and outcome of systemic paraphenylene diamine (PPD) intoxication. METHODS:Our study was retrospective. It was conducted over 6 yrs (1994-2000) in the medical intensive care unit (ICU) of a university hospital and it concerned 19 patients hospitalized for systemic PPD intoxication...

journal_title：Journal of nephrology

authors： Kallel H,Chelly H,Dammak H,Bahloul M,Ksibi H,Hamida CB,Chaari A,Rekik N,De Broe ME,Bouaziz M

更新日期：2005-05-01 00:00:00

abstract：:Given the alarming predictions of the potentially devastating future epidemic of end-stage renal disease (ESRD), further knowledge is still urgently needed on this topic. The real dimensions of the problem are still unclear. It is difficult to compare Europe and the USA because different criteria are used in data coll...

journal_title：Journal of nephrology

authors： Gambaro G,D'Angelo A,Conte M,Bonfante L,De Biase V,Lupo A

更新日期：2005-03-01 00:00:00

abstract：:Von Hippel-Lindau (VHL) disease is a rare autosomal dominant disorder characterized by multifocal and bilateral renal cell carcinoma and cysts, retinal angiomas, hemangioblastoma of the central nervous system, pheochromocytoma, epididymis cystoadenoma, pancreatic cysts and/or islet cell tumors. However, phenotypic man...

journal_title：Journal of nephrology

authors： Sessa A,Battini G,Meroni M,Pitingolo F,Righetti M,Ciotti P,Di Maria E,Bellone E,Ajmar F,Mandich P

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is an established risk factor for cardiovascular disease (CVD). In addition, patients with renal disease are exposed to a myriad of risk factors that increase their risk even further. The treatment of risk factors in these patients is paramount to reducing cardiovascular risk and...

journal_title：Journal of nephrology

authors： Van Zuilen AD,Wetzels JF,Blankestijn PJ,Bots ML,Van Buren M,Ten Dam MA,Kaasjager KA,Van De Ven PJ,Vleming LJ,Ligtenberg G,Ligtenberg G,MASTERPLAN Study Group.

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Recently, some studies have emphasized the role of plasma 25-(OH)vitamin D (25OHD) levels in mineral metabolism dysregulation in chronic kidney diseases (CKDs). However, to date little attention has been paid to 25OHD metabolism abnormalities after renal transplantation (Tx). This cross-sectional study aimed...

journal_title：Journal of nephrology

authors： Lomonte C,Antonelli M,Vernaglione L,Cazzato F,Casucci F,Chimienti D,Bruno A,Cocola S,Verrelli EA,Basile C

更新日期：2005-01-01 00:00:00

abstract：:The pathogenesis of calcium-oxalate (CaOx) renal stones is still debated and a number of issues needs to be clarified. In particular, it is difficult to combine the intraluminal physical-chemical imbalance and fixed particle theory with the evidence that CaOx stones actually form and grow on Randall's plaque in the re...

journal_title：Journal of nephrology

authors： Gambaro G,D'Angelo A,Fabris A,Tosetto E,Anglani F,Lupo A

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:This study aimed to evaluate the health-related quality of life (HRQOL) and burden on family caregivers of chronic dialysis patients and to analyze which factors were associated with it. METHODS:A cross-sectional multicentric study was carried out with 221 patient/caregiver pairs. General population Short F...

journal_title：Journal of nephrology

authors： Alvarez-Ude F,Valdés C,Estébanez C,Rebollo P,FAMIDIAL Study Group.

更新日期：2004-11-01 00:00:00

abstract：:Rapidly progressive glomerulonephritis (RPGN) must be diagnosed and treated quickly to prevent irreversible organ injury. The commonest cause of RPGN is anti-neutrophil cytoplasm antibody (ANCA) associated small vessel vasculitis, and the most severe is anti-glomerular basement membrane (GBM) antibody disease. In this...

journal_title：Journal of nephrology

authors： Little MA,Pusey CD

更新日期：2004-11-01 00:00:00

abstract：:It has been increasingly apparent that end-stage renal disease (ESRD) patients carry an inflammatory burden, which may play a pivotal role in the evolution of not only wasting but also of the massive increase in the relative risk of cardiovascular disease (CVD). Also increased oxidative stress (an impairment of the pr...

journal_title：Journal of nephrology

authors： Maruyama Y,Lindholm B,Stenvinkel P

更新日期：2004-11-01 00:00:00

abstract：:Ambulatory blood pressure monitoring (ABPM) has been developed to overcome recognized deficiencies and inaccuracies of classic (office) BP measurements in the diagnosis and management of hypertension (HTN). Although in adults it has become a valuable tool for the diagnosis and ongoing management of HTN, and its use ha...

journal_title：Journal of nephrology

authors： Gavrilovici C,Goldsmith DJ,Reid C,Gubeth-Tatomir P,Covic A

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:The most frequent cause of death in hemodialysis (HD) patients is cardiovascular disease (CVD), and chronic inflammation has been identified as an epidemiologically important risk factor for CVD. Elevated levels of minor acute phase reactants, such as ceruloplasmin (Cp) and transferrin, have been related to ...

journal_title：Journal of nephrology

authors： Panichi V,Taccola D,Rizza GM,Consani C,Migliori M,Filippi C,Paoletti S,Sidoti A,Borracelli D,Panicucci E,Giovannini L

更新日期：2004-09-01 00:00:00

abstract：:Renal fibrogenesis can be induced by several injury mechanisms in different renal diseases, but ultimately produces identical fibrotic changes in the kidney. Recently, a number of agents that can inhibit extracellular matrix (ECM) accumulation have been studied, suggesting a therapeutic utility in the treatment of fib...

journal_title：Journal of nephrology

authors： Negri AL

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:The risks connected with dialysis fluid contamination are well established. Epidemiological studies have demonstrated just how difficult it is to obtain permanently satisfactory quality standards. Therefore, dialysis centers must have effective and regular quality control programs, particularly with the grow...

journal_title：Journal of nephrology

authors： Pizzarelli F,Cerrai T,Biagini M,Malaguti M,Bargagna R

更新日期：2004-07-01 00:00:00

abstract：:Marcello Malpighi was born in Crevalcore on March 10, 1628 and died in Rome on July 25, 1694. In Bologna he had among his opponents Giovanni Gerolamo Sbaraglia and Paoli Mini who prevented him being appointed to the chair of anatomy. This paper describes the reasons for this long term debate. ...

journal_title：Journal of nephrology

authors： Campieri C,Persici E,Stefoni S

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Detailed analyses on crush syndrome resulting from earthquakes is scarce. This study aimed to analyze the effect of gender on clinical course of the renal victims of the catastrophic Marmara earthquake that struck Northwestern Turkey in 1999. METHODS:Questionnaires were prepared within the first week of dis...

journal_title：Journal of nephrology

authors： Sever MS,Erek E,Vanholder R,Lameire N

更新日期：2004-05-01 00:00:00

abstract：:Jaundice and pancreatitis are serious complications in post renal transplantations; hepatotropic viruses and drugs are commonly implicated. We describe ascaris infestation causing pancreatitis and obstructive jaundice in a renal transplant patient. ...

journal_title：Journal of nephrology

authors： Sunil P,Tribhuvan G,Anil M

更新日期：2004-05-01 00:00:00

abstract：:Survival analysis is the statistical method for studying the time between entry to a study and a subsequent event. Survival is often the most important outcome in both observational and intervention studies. The analysis of survival, however, is not simple because of a number of factors. The time between entry to a st...

journal_title：Journal of nephrology

authors： Khan IH,Prescott GJ

更新日期：2004-03-01 00:00:00

abstract：:To determine the clinical impact of conversion from C0 to C2 Neoral monitoring, we conducted a 6-month prospective study in 62 stable renal transplant recipients. Neoral was given alone (19%), with steroids (31%), combined with azathioprine (Aza) or mycophenolate mofetil (MMF) (50%). C0 and C2 target ranges were, resp...

journal_title：Journal of nephrology

authors： Sandrini S,Bossini N,Setti G,Mazzucchelli C,Maiorca P,Cancarini G

更新日期：2004-03-01 00:00:00

abstract：:The relevance of the Salerno Medical School is examined through the contributions of Magister Maurus, Alfano I, Giovanni Plateario, Giovanni Afflacio, Bartolomeo and Urso of Calabria. An unpublished treatise on De Urinis in middlelatin and Italian volgare is introduced here for the first time by discussing the lapis o...

journal_title：Journal of nephrology

authors： Oldoni M

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Arteriovenous (AV) fistulas are crucial in patients requiring long-term hemodialysis (HD). Dysfunctions of these fistulas are the most common causes of recurrent hospitalizations. This study aimed to evaluate the feasibility, safety and usefulness of contrast-enhanced magnetic resonance angiography (CE-MRA) ...

journal_title：Journal of nephrology

authors： Paksoy Y,Gormus N,Tercan MA

更新日期：2004-01-01 00:00:00

abstract：:Rapidly progressive glomerulonephritis (RPGN) is a rare occurrence in IgA nephropathy (IgAN) in renal transplant patients on immunosuppressive therapy. RPGN post ischemia-reperfusion has not been previously reported. We report a 62 year old male patient on azathioprine therapy, 9 years after left cadaveric renal trans...

journal_title：Journal of nephrology

authors： Tovbin D,Shnaider A,Kachko L,Basok A,Vorobiov M,Rogachev B,Abramov D,Zlotnik M

更新日期：2004-01-01 00:00:00

abstract：:One of the central functions of the kidney is to excrete low molecular weight, water soluble, plasma, waste products into the urine, whereas macromolecules, the size of albumin and larger, are retained. The flow of the glomerular filtrate is thought to follow an extracellular route, passing through the endothelial fen...

journal_title：Journal of nephrology

authors： Nosadini R,Tonolo G

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Numerous data support the possible role of myeloblastin/proteinase 3 (PR3) in growth and differentiation of neutrophil granulocytes and certain monocyte subtypes. However, whether PR3 is expressed in non-myeloid cells remains a matter of debate even though recent studies clearly demonstrated its expression i...

journal_title：Journal of nephrology

authors： Relle M,Mayet WJ,Strand D,Brenner W,Galle PR,Schwarting A

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:NKF K-DOQI clinical practice guidelines recommend a regular monitoring of vascular access (VA) through several methods, such as VA recirculation (AR). Assessment of AR is crucial to avoid inefficiency of hemodialysis (HD). A non-urea based method has been developed (ultrasound dilution Transonics Hemodialysi...

journal_title：Journal of nephrology

authors： Basile C,Ruggieri G,Vernaglione L,Montanaro A,Giordano R

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:This study investigated whether modifications of placental expression of endothelin-1 (ET-1), nitric oxide synthase (NOS) and tissue factor (TF) are associated with abnormal Doppler waveforms. METHODS:Fourteen pre-term severe preeclamptic (PE) women with fetal growth restriction (FGR) and 14 normal preg nan...

journal_title：Journal of nephrology

authors： Di Paolo S,Volpe P,Grandaliano G,Stallone G,Schena A,Greco P,Resta L,Selvaggi L,Cincione R,Schena FP,Gesualdo L

更新日期：2003-09-01 00:00:00

abstract：:Sarcoidosis is a multisystem disorder of unknown etiology, which may occur in all tissues and organs of the body. Clinical presentation may be quite variable and affected by race. The most commonly affected system is the lungs with >95% of patients displaying such involvement. Renal involvement is uncommon (<2%) and m...

journal_title：Journal of nephrology

authors： Carmichael P,O'Donnell JP

更新日期：2003-09-01 00:00:00

abstract：UNLABELLED:The prognosis of renal survival in both type 1 and type 2 diabetes mellitus is not benign. Several factors characterize the increase in the risk of developing renal damage in diabetic patients, distinguished in diabetes-related factors, genetic factors and other factors. DIAGNOSIS:Diagnosis requires standar...

journal_title：Journal of nephrology

authors： Strippoli GF,Di Paolo S,Cincione R,Di Palma AM,Teutonico A,Grandaliano G,Schena FP,Gesualdo L

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:The ongoing necessity for systemic heparinization is a well-known disadvantage of continuous renal replacement therapies (CRRT), and alternative methods of anticoagulation may be required. Our aim was to evaluate, in patients with a high risk of bleeding, the possibility of an acceptable filter life with non...

journal_title：Journal of nephrology

authors： Morabito S,Guzzo I,Solazzo A,Muzi L,Luciani R,Pierucci A

更新日期：2003-07-01 00:00:00

abstract：:Page kidney was first described in animal experiments in 1939. In the 1950s and 1960s the human counterpart became evident. In this review we examine the modest literature on this rare but important renal/urological complication, summarize the clinical features, and discuss the best approach to diagnosis and managemen...

journal_title：Journal of nephrology

authors： Haydar A,Bakri RS,Prime M,Goldsmith DJ

更新日期：2003-05-01 00:00:00